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AstraZeneca GmbH

Director, Solid Tumor TI/TV, Oncology R&D

AstraZeneca GmbH, Gaithersburg, Maryland, us, 20883


Director, Solid Tumor TI/TV, Oncology R&D

Hit Apply below to send your application for consideration Ensure that your CV is up to date, and that you have read the job specs first.Do you feel passionate about the possibilities of great science changing lives of cancer patients? Do you have a background within oncology research in target identification/validation and cancer biology, and have interest in finding new targets for AZ’s growing portfolio of ADCs and Radioimmunoconjugates? If so, this may be the role for you.We currently have an exciting opportunity for a highly motivated

Director

to lead a team of scientists across multiple AZ sites spearheading solid tumor target discovery, validation, and biology.Within AstraZeneca Oncology R&D, we are committed to advancing the science to deliver life-changing medicines to patients most in need. With a combination-focused pipeline that exploits the power of six scientific platforms (Immuno-Oncology, Tumor Drivers and Resistance, DNA Damage Response, Antibody-drug Conjugates, Cell Therapy and Epigenetics) to help address unmet clinical needs in a host of cancers, we are motivated by a dedication to the scientific discovery and teamwork that will one day help eliminate cancer as a cause of death.What you’ll doWe are seeking a

Director in Oncology Targeted Discovery

(OTD) to develop a comprehensive strategy to discover and validate new targets for ADCs and RICs, as well as understand the role of targets in cancer biology. Working in partnership with the OTD team across the globe, lead the implementation of novel target biology and discovery efforts.ResponsibilitiesLead a team across multiple sites focused on cancer biology-based target discovery and validation for ADCs and RICsCollaborate with internal teams to prioritize targets, develop target identification and validation strategiesSupport project teams with early validation work and exploration of target biologyInterface with Tumor Councils and strategy teams to provide scientific leadership and gain feedback for ADC developmentLead internal and external research collaborations supporting target discovery and biologyEssential for the rolePhD and/or MD with experience in drug developmentA minimum of 6 years of relevant experienceIn-depth knowledge of tumor target identification strategies utilizing OMICS and functional screensComprehensive knowledge of ADCs and oncology disease area biology (solid tumors); experience with ADCs is desirableAbility to drive, manage, execute and deliver results for complex multi-functional projectsHighly developed problem solving and risk management skills, with attention to detailHighly developed collaborative working skillsAbility to act as an external ambassador and to influence external organizations to enhance the image and reputation of AstraZenecaEstablished ability to lead a mid-size team including setting goals and objectives, empowering and developing team membersDesirable for the roleExperience in target identification/validation for mAb therapeutics or ADCs in oncology.Ready to join us in our mission? Apply now!

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