AbbVie, Inc
Scientist I, Drug Product Design and Development
AbbVie, Inc, North Chicago, Illinois, us, 60086
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job Description
The Drug Product Design and Development (DPDD) group within the Small Molecule CMC organization is responsible for designing and developing formulations that enable delivery of AbbVie's candidate molecules in a dosage form for clinical evaluation during early development. DPDD is also accountable for developing drug products for Phase 3 clinical study and advancing for product commercialization.
AbbVie's DPDD is seeking a highly motivated, talented, and creative scientist with a proven track record in the design and characterization of solid oral dosage forms. We have a challenging opportunity for a Senior Scientist based in North Chicago, IL. The primary role for this position is to serve as formulation lead. The person will be working with cross-functional development partners to develop stage appropriate drug products to support clinical development. The desired candidate will have a strong background and hands-on experience in formulation design, characterization, and process development.
Key responsibilities include:
* Lead the formulation design for small molecule development candidates within the AbbVie pipeline.* Interface to drug product development teams to ensure that biopharmaceutical and physicochemical considerations are incorporated into formulation design.* Advance scientific expertise within function. Proactively demonstrate leadership by advising and sharing knowledge and expert opinions with subordinates, peers, and senior management.* Ensure development of technologies and scientific innovation that improve the capability to formulate small molecules within the AbbVie pipeline* Collaborate with other functions within AbbVie to align
The Drug Product Design and Development (DPDD) group within the Small Molecule CMC organization is responsible for designing and developing formulations that enable delivery of AbbVie's candidate molecules in a dosage form for clinical evaluation during early development. DPDD is also accountable for developing drug products for Phase 3 clinical study and advancing for product commercialization. We have an exciting opportunity for a Scientist I/Scientist II position in North Chicago, IL. We are seeking a highly motivated and collaborative scientist with strong background and hands-on experiences in parenteral and/or oral formulations. The primary role for this position is to support lab-based development activities related to parenteral and oral formulations including nano and microparticle-based drug products such as lipid nanoparticles or long acting injectables.
Key responsibilities include:
* Independently design and conduct critical experiments that further project goals.* Interpret results and draw conclusions from own multistage experiments, note significant deviations, then suggest, design, and pursue relevant experiments.* Implement and may innovate new experimental protocols.* Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.* Demonstrate a high level of proficiency in his/her field.* Understand the goal and maintain a high proficiency in his/her projects as well as the overall program* Perform routine and complex tasks competently and independently and generate reliable and consistent results.* Impact projects mostly through lab and/or pilot plant-based activities where applicable.* a broad range of strategies that directly support development programs* Ensure compliance with AbbVie safety, quality and regulatory policies and government regulations
Qualifications
Basic:
* Scientist I: MS (typically 2+ years of experience) or BS (typically 5+ years of experience), Scientist II: MS (typically 5+ years of experience) or BS (typically 7+ years of experience), in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or Chemical Engineering or equivalent disciplines.* Ability to independently design, execute and interpret experiments to answer scientific questions.* Ability to learn, understand and master new experimental techniques.* Ability to multitask and work within timelines.* Scientific writing skills and strong verbal communication skills.* Ability to work collaboratively in a cross-functional team setting.
Preferred:
* Experience in utilizing preparation methods for parenteral formulations (microfluidic technology, thin-film-hydration, single/double emulsions using probe sonication and homogenization, nanoprecipitation, wet milling, etc.) and analytical techniques and instruments (i.e., DLS, laser diffraction, HPLC, DSC, TGA, etc.) for characterization of pharmaceutical dosage forms.* Experience in the characterization of particulate based formulations.* Familiarity with GSP, GLP, GMP.
Key AbbVie Competencies:
* Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.* Learns fast, grasps the "essence" and can change the course quickly where indicated.* Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.* Raises the bar and is never satisfied with the status quo.* Creates a learning environment, open to suggestions and experimentation for improvement.* Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
* The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
* We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
* This job is eligible to participate in our short-term incentive programs.
* This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status
Job Description
The Drug Product Design and Development (DPDD) group within the Small Molecule CMC organization is responsible for designing and developing formulations that enable delivery of AbbVie's candidate molecules in a dosage form for clinical evaluation during early development. DPDD is also accountable for developing drug products for Phase 3 clinical study and advancing for product commercialization.
AbbVie's DPDD is seeking a highly motivated, talented, and creative scientist with a proven track record in the design and characterization of solid oral dosage forms. We have a challenging opportunity for a Senior Scientist based in North Chicago, IL. The primary role for this position is to serve as formulation lead. The person will be working with cross-functional development partners to develop stage appropriate drug products to support clinical development. The desired candidate will have a strong background and hands-on experience in formulation design, characterization, and process development.
Key responsibilities include:
* Lead the formulation design for small molecule development candidates within the AbbVie pipeline.* Interface to drug product development teams to ensure that biopharmaceutical and physicochemical considerations are incorporated into formulation design.* Advance scientific expertise within function. Proactively demonstrate leadership by advising and sharing knowledge and expert opinions with subordinates, peers, and senior management.* Ensure development of technologies and scientific innovation that improve the capability to formulate small molecules within the AbbVie pipeline* Collaborate with other functions within AbbVie to align
The Drug Product Design and Development (DPDD) group within the Small Molecule CMC organization is responsible for designing and developing formulations that enable delivery of AbbVie's candidate molecules in a dosage form for clinical evaluation during early development. DPDD is also accountable for developing drug products for Phase 3 clinical study and advancing for product commercialization. We have an exciting opportunity for a Scientist I/Scientist II position in North Chicago, IL. We are seeking a highly motivated and collaborative scientist with strong background and hands-on experiences in parenteral and/or oral formulations. The primary role for this position is to support lab-based development activities related to parenteral and oral formulations including nano and microparticle-based drug products such as lipid nanoparticles or long acting injectables.
Key responsibilities include:
* Independently design and conduct critical experiments that further project goals.* Interpret results and draw conclusions from own multistage experiments, note significant deviations, then suggest, design, and pursue relevant experiments.* Implement and may innovate new experimental protocols.* Understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner.* Demonstrate a high level of proficiency in his/her field.* Understand the goal and maintain a high proficiency in his/her projects as well as the overall program* Perform routine and complex tasks competently and independently and generate reliable and consistent results.* Impact projects mostly through lab and/or pilot plant-based activities where applicable.* a broad range of strategies that directly support development programs* Ensure compliance with AbbVie safety, quality and regulatory policies and government regulations
Qualifications
Basic:
* Scientist I: MS (typically 2+ years of experience) or BS (typically 5+ years of experience), Scientist II: MS (typically 5+ years of experience) or BS (typically 7+ years of experience), in Pharmaceutics, Pharmaceutical Sciences, Chemistry, or Chemical Engineering or equivalent disciplines.* Ability to independently design, execute and interpret experiments to answer scientific questions.* Ability to learn, understand and master new experimental techniques.* Ability to multitask and work within timelines.* Scientific writing skills and strong verbal communication skills.* Ability to work collaboratively in a cross-functional team setting.
Preferred:
* Experience in utilizing preparation methods for parenteral formulations (microfluidic technology, thin-film-hydration, single/double emulsions using probe sonication and homogenization, nanoprecipitation, wet milling, etc.) and analytical techniques and instruments (i.e., DLS, laser diffraction, HPLC, DSC, TGA, etc.) for characterization of pharmaceutical dosage forms.* Experience in the characterization of particulate based formulations.* Familiarity with GSP, GLP, GMP.
Key AbbVie Competencies:
* Builds strong relationships with peers and cross functionally with partners outside of the team to enable higher performance.* Learns fast, grasps the "essence" and can change the course quickly where indicated.* Connects ideas from disparate fields, integrates data and information quickly, and takes risks to achieve the highest performance.* Raises the bar and is never satisfied with the status quo.* Creates a learning environment, open to suggestions and experimentation for improvement.* Embraces the ideas of others, nurtures innovation and manages innovation to reality.
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
* The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
* We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
* This job is eligible to participate in our short-term incentive programs.
* This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie's policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status