Generate Biomedicines
Executive Director, Computational Protein Design Generation
Generate Biomedicines, Somerville, Massachusetts, us, 02143
About Generate:Biomedicines:
Generate:Biomedicines is a new kind of therapeutics company - existing at the intersection of machine learning, biological engineering, and medicine - pioneering Generative Biology to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.
We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!
Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received nearly $700 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with over 275 employees.
The Role:
Generate:Biomedicines (Generate) is seeking an exceptional leader to serve as the Head of Computational Protein Generation (CPG). This pivotal role is at the heart of our mission, bringing together multiple disciplines across the drug discovery pipeline. The CPG team designs therapeutic molecules for all of our drug programs, and so operates at the intersection of state-of-the-art machine learning advancements, cutting-edge wet lab technologies, and therapeutic innovation. The successful candidate will lead a highly interdisciplinary team, collaborating and strategizing closely with deep experts across various domains at Generate to drive the development of therapeutic molecules. The candidate will also lead an impactful research agenda to achieve unprecedented scale in molecular generation.
Here's how you will contribute:
* Team Leadership: Lead and mentor the CPG team, supporting their professional growth fostering a collaborative and high-performance culture that encourages innovation and excellence.* Cross-functional Collaboration: Interface with therapeutic program teams to plan and execute projects, ensuring alignment with strategic objectives.* Technology Integration: Collaborate with Machine Learning and Data Science groups to incorporate the latest generative technologies into program applications.* Strategic Alignment: Report to and work closely with the CTO to ensure the team's execution and operations are strategically and technologically aligned with company goals.* Infrastructure Development: Partner with Digital and Engineering teams to establish robust infrastructure supporting automation, data analysis, and consistent design protocols.* Operational Excellence: Drive execution-focused initiatives, ensuring operational efficiency and clarity in how the team functions and the delivery of high-quality molecular designs.* Innovation Advocate: Promote the adoption of cutting-edge technologies and methodologies, driving continuous improvement and innovation within the team.
The Ideal Candidate will have:
* Educational Background: PhD in Computational Biology, Bioinformatics, Biophysics, Computer Science, or a related field.* Experience: At least 10 years of relevant experience, including leadership roles managing multi-functional teams within therapeutics: Deep understanding of computational protein design, machine learning applications in molecular biology, and wet-lab integration.* Cross-disciplinary Collaboration: Proven track record of working effectively with therapeutic program teams, data science, engineering, and executive leadership.* Strategic Thinking: Ability to align team operations with broader organizational strategies and technological advancements.* Execution Focused: Demonstrated ability to drive projects to completion with high quality, operational efficiency, and impact.* People Leadership: Strong skills in mentoring, team development, and fostering a collaborative team environment.* Communication Skills: Excellent verbal and written communication abilities, capable of conveying complex technical information clearly and effectively.
#LI-HM1
Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
COVID Safety:
Generate:Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster. The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations. The Company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.
Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.
Generate:Biomedicines is a new kind of therapeutics company - existing at the intersection of machine learning, biological engineering, and medicine - pioneering Generative Biology to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.
We pursue this audacious vision because we believe in the unique and revolutionary power of generative biology to radically transform the lives of billions, with an outsized opportunity for patients in need. We are seeking collaborative, relentless problem solvers that share our passion for impact to join us!
Generate:Biomedicines was founded in 2018 by Flagship Pioneering and has received nearly $700 million in funding, providing the resources to rapidly scale the organization. The Company has offices in Somerville and Andover, Massachusetts with over 275 employees.
The Role:
Generate:Biomedicines (Generate) is seeking an exceptional leader to serve as the Head of Computational Protein Generation (CPG). This pivotal role is at the heart of our mission, bringing together multiple disciplines across the drug discovery pipeline. The CPG team designs therapeutic molecules for all of our drug programs, and so operates at the intersection of state-of-the-art machine learning advancements, cutting-edge wet lab technologies, and therapeutic innovation. The successful candidate will lead a highly interdisciplinary team, collaborating and strategizing closely with deep experts across various domains at Generate to drive the development of therapeutic molecules. The candidate will also lead an impactful research agenda to achieve unprecedented scale in molecular generation.
Here's how you will contribute:
* Team Leadership: Lead and mentor the CPG team, supporting their professional growth fostering a collaborative and high-performance culture that encourages innovation and excellence.* Cross-functional Collaboration: Interface with therapeutic program teams to plan and execute projects, ensuring alignment with strategic objectives.* Technology Integration: Collaborate with Machine Learning and Data Science groups to incorporate the latest generative technologies into program applications.* Strategic Alignment: Report to and work closely with the CTO to ensure the team's execution and operations are strategically and technologically aligned with company goals.* Infrastructure Development: Partner with Digital and Engineering teams to establish robust infrastructure supporting automation, data analysis, and consistent design protocols.* Operational Excellence: Drive execution-focused initiatives, ensuring operational efficiency and clarity in how the team functions and the delivery of high-quality molecular designs.* Innovation Advocate: Promote the adoption of cutting-edge technologies and methodologies, driving continuous improvement and innovation within the team.
The Ideal Candidate will have:
* Educational Background: PhD in Computational Biology, Bioinformatics, Biophysics, Computer Science, or a related field.* Experience: At least 10 years of relevant experience, including leadership roles managing multi-functional teams within therapeutics: Deep understanding of computational protein design, machine learning applications in molecular biology, and wet-lab integration.* Cross-disciplinary Collaboration: Proven track record of working effectively with therapeutic program teams, data science, engineering, and executive leadership.* Strategic Thinking: Ability to align team operations with broader organizational strategies and technological advancements.* Execution Focused: Demonstrated ability to drive projects to completion with high quality, operational efficiency, and impact.* People Leadership: Strong skills in mentoring, team development, and fostering a collaborative team environment.* Communication Skills: Excellent verbal and written communication abilities, capable of conveying complex technical information clearly and effectively.
#LI-HM1
Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
COVID Safety:
Generate:Biomedicines enforces a mandatory vaccination policy for COVID-19. All employees must be fully vaccinated and have received a booster. The purpose of this policy is to safeguard the health of our employees, their families, and the community at large from infectious disease that may be reduced by vaccinations. The Company will make exceptions to this policy if required by applicable law and will consider requests for an exemption from this policy due to a medical reason, or because of a sincerely held religious belief, or any other exemptions that may be recognized by applicable.
Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.